Title:
タンパク質複合体及び該タンパク質複合体を含むワクチン組成物の生産方法
Document Type and Number:
Japanese Patent JP2014510093
Kind Code:
A
Abstract:
The present invention relates to methods for the production of heat shock protein complexes for use in vaccine compositions. In particular, there is provided a method for increasing the level and immunogenicity of heat shock protein complexes produced in cells by subjecting the cells to specific stress inducing stimuli. The invention further extends to the use of heat shock protein complexes produced according to the methods of the invention in the preparation of vaccine compositions for the prevention and treatment of infectious diseases and cancerous conditions.
Inventors:
Camilo Coraco
Ian McEntee
Ian McEntee
Application Number:
JP2014500473A
Publication Date:
April 24, 2014
Filing Date:
March 23, 2012
Export Citation:
Assignee:
Immunobiology Limited
International Classes:
C07K19/00; A61K39/00; A61K39/02; A61K39/12; A61K39/385; A61P31/00; A61P31/04; A61P31/12; A61P35/00; C07K14/00; C07K14/82
Domestic Patent References:
| JP2003507431A | 2003-02-25 | |||
| JP2003527322A | 2003-09-16 | |||
| JP2002523376A | 2002-07-30 | |||
| JP2003507431A | 2003-02-25 |
Foreign References:
| WO2010146401A1 | 2010-12-23 | |||
| WO2001063278A2 | 2001-08-30 | |||
| WO2009148608A1 | 2009-12-10 | |||
| WO2010146401A1 | 2010-12-23 |
Attorney, Agent or Firm:
Kenji Sugimura
Hitomi Yuki
Koichiro God
Hitomi Yuki
Koichiro God