Title:
TRPM8アンタゴニストおよび治療におけるそれらの使用
Document Type and Number:
Japanese Patent JP2014517074
Kind Code:
A
Abstract:
Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
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Inventors:
Brown, the ames
Chiang, Jian Jei
Gore, Bizay Keshyab
Harryd, scott
Horn, daniel bee
Color, Machine Earl
Liu, Ching Yen
Monensya Inn, Holger
Nguyen, Thomas Tay
Nobuko Nishimura
Chiyeon, Wenji
Chiang, Jian Jei
Gore, Bizay Keshyab
Harryd, scott
Horn, daniel bee
Color, Machine Earl
Liu, Ching Yen
Monensya Inn, Holger
Nguyen, Thomas Tay
Nobuko Nishimura
Chiyeon, Wenji
Application Number:
JP2014517171A
Publication Date:
July 17, 2014
Filing Date:
June 21, 2012
Export Citation:
Assignee:
Amjien Incorporated
International Classes:
C07D213/40; A61K31/435; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4709; A61K31/5377; A61P1/02; A61P1/04; A61P3/10; A61P9/00; A61P11/00; A61P11/02; A61P11/06; A61P13/00; A61P13/10; A61P15/00; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P19/08; A61P25/00; A61P25/04; A61P25/06; A61P25/22; A61P25/24; A61P27/02; A61P29/00; A61P31/22; A61P37/08; A61P43/00; C07D213/61; C07D213/64; C07D213/75; C07D401/12; C07D401/14; C07D405/12; C07D409/12; C07D413/12
Attorney, Agent or Firm:
Kawaguchi International Patent Office