Title:
USEFUL SUBSTANCE SPECIFIC PRODUCTION RATE PROMOTER, AND VIABILITY DECREASE INHIBITOR IN CELLS
Document Type and Number:
Japanese Patent JP2019180395
Kind Code:
A
Abstract:
To provide methods for further improving the specific production rate of useful substances such as proteins in cells.SOLUTION: Provided is a specific production rate promoter for useful substances in cells, containing a component having protein kinase inhibitory activity; a viability decrease inhibitor in cells, containing a component having protein kinase inhibitory activity; a cell culture medium used for producing a useful substance comprising the specific production rate promoter or the viability decrease inhibitor; and a method for producing a useful substance comprising culturing cells using a cell culture medium containing the specific production rate promoter or the viability decrease inhibitor.SELECTED DRAWING: Figure 1
Inventors:
KIDO MASAHIDE
NISHIKAWA KOJI
NISHIKAWA KOJI
Application Number:
JP2019050543A
Publication Date:
October 24, 2019
Filing Date:
March 19, 2019
Export Citation:
Assignee:
OSAKA SODA CO LTD
International Classes:
C12N1/38; C12P21/08
Domestic Patent References:
| JPH0427397A | 1992-01-30 | |||
| JP2017132743A | 2017-08-03 |
Foreign References:
| US20050142621A1 | 2005-06-30 |
Other References:
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GRANDMAISON P A. ET AL.: "Externalization of phosphatidylserine during apoptosis does not specifically require either isoform", BIOCHIM BIOPHYS ACTA, vol. 1636, JPN6022050230, 2004, pages 1 - 11, XP004492616, ISSN: 0004992580, DOI: 10.1016/j.bbalip.2003.11.004
MULVEY C S. ET AL.: "Wavelength-dependent backscattering measurements for quantitative real-time monitoring of apoptosis", J BIOMED OPT, vol. Vol. 14(6):064013, JPN6022050233, 2009, ISSN: 0004992581
"キナーゼ阻害剤とホスファターゼ阻害剤", MERCK MILLIPORE CORPORATION[ONLINE], JPN6022050234, 6 September 2016 (2016-09-06), ISSN: 0004992582