Title:
PRODUCTION METHOD OF DIABETES MODEL ANIMAL, AND DIABETES MODEL ANIMAL
Document Type and Number:
Japanese Patent JP2020031551
Kind Code:
A
Abstract:
To provide a model animal useful for spontaneous generation type diabetes; and to provide a production method thereof.SOLUTION: A production method of a diabetes model animal includes a culture process for culturing a fertilized embryo of a non-human animal by a prescribed culture solution, a transplantation process for transplanting the cultured embryo to a foster parent of a non-human animal, and a production process for producing a child from the foster parent.SELECTED DRAWING: Figure 1
Inventors:
KISHIGAMI TETSUSHI
MOCHIZUKI KAZUKI
WAKAYAMA TERUHIKO
MOCHIZUKI KAZUKI
WAKAYAMA TERUHIKO
Application Number:
JP2018159174A
Publication Date:
March 05, 2020
Filing Date:
August 28, 2018
Export Citation:
Assignee:
UNIV YAMANASHI
International Classes:
A01K67/027
Other References:
CALLE, A. ET AL.: "Male mice produced by in vitro culture have reduced fertility and transmit organomegaly and glucose", BIOLOGY OF REPRODUCTION, vol. 87, JPN6022025792, 2012, pages 34 - 1, ISSN: 0004822856
RAMIREZ-PEREZ, F. I. ET AL.: "Effects of the use of assisted reproductive technologies and an obesogenic environment on resistance", PLOS ONE, vol. 9, JPN6022025786, 2014, pages 112651, ISSN: 0004822857
CERNY, D. ET AL.: "Assisted Reproductive Technologies Predispose to Insulin Resistance and Obesity in Male Mice Challen", ENDOCRINOLOGY, vol. 158, JPN6022025787, 2017, pages 1152 - 1159, ISSN: 0004822858
WATKINS, A. J. ET AL.: "Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104, JPN6022025788, 2007, pages 5449 - 5454, ISSN: 0004822859
SCOTT, K. A. ET AL.: "Glucose parameters are altered in mouse offspring produced by assisted reproductive technologies and", BIOLOGY OF REPRODUCTION, vol. 83, JPN6022025789, 2010, pages 220 - 227, ISSN: 0004822860
OLAR, T. T. ET AL.: "Effects of medium composition on murine and human blastocyst formation and hatching rate", JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, vol. 10, JPN6022025790, 1993, pages 192 - 196, ISSN: 0004822861
RAMIREZ-PEREZ, F. I. ET AL.: "Effects of the use of assisted reproductive technologies and an obesogenic environment on resistance", PLOS ONE, vol. 9, JPN6022025786, 2014, pages 112651, ISSN: 0004822857
CERNY, D. ET AL.: "Assisted Reproductive Technologies Predispose to Insulin Resistance and Obesity in Male Mice Challen", ENDOCRINOLOGY, vol. 158, JPN6022025787, 2017, pages 1152 - 1159, ISSN: 0004822858
WATKINS, A. J. ET AL.: "Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104, JPN6022025788, 2007, pages 5449 - 5454, ISSN: 0004822859
SCOTT, K. A. ET AL.: "Glucose parameters are altered in mouse offspring produced by assisted reproductive technologies and", BIOLOGY OF REPRODUCTION, vol. 83, JPN6022025789, 2010, pages 220 - 227, ISSN: 0004822860
OLAR, T. T. ET AL.: "Effects of medium composition on murine and human blastocyst formation and hatching rate", JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, vol. 10, JPN6022025790, 1993, pages 192 - 196, ISSN: 0004822861