Title:
MARKERS FOR IDENTIFYING CALORIC RESTRICTION AND CALORIC RESTRICTION MIMETICS
Document Type and Number:
Japanese Patent JP2021052803
Kind Code:
A
Abstract:
To provide markers of caloric restriction (CR).SOLUTION: Markers of caloric restriction (CR) can be identified in a selected tissue by exposing an animal to CR conditions and selecting one or more genes differentially expressed in response to CR conditions in multiple subject groups. A candidate compound can be screened for likely ability to mimic the effects of CR when administered to an animal by comparing the tissue levels of expression products of the genes in animals treated with the candidate compound to those of animals subjected to CR.SELECTED DRAWING: Figure 1
Inventors:
ANGELA MASTALOUDIS
STEVE WOOD
TOMAS ALVERTO PROLLA
JAMIE LOUIS BARGER
RICHARD WEINDRUCH
CHANG JOSEPH
STEVE WOOD
TOMAS ALVERTO PROLLA
JAMIE LOUIS BARGER
RICHARD WEINDRUCH
CHANG JOSEPH
Application Number:
JP2021002732A
Publication Date:
April 08, 2021
Filing Date:
January 12, 2021
Export Citation:
Assignee:
NSE PRODUCTS INC
International Classes:
C12N15/12
Domestic Patent References:
| JP2008524256A | 2008-07-10 | |||
| JP2006521809A | 2006-09-28 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto