Title:
【発明の名称】生物学的に活性な殺菌性/透過性増大蛋白質断片
Document Type and Number:
Japanese Patent JP3086685
Kind Code:
B2
Abstract:
A biologically active polypeptide fragment of mammalian bactericidal/permeability increasing proteins is provided. Also provided are methods for isolating the fragments and methods for employing the polypeptide fragments as antimicrobial agents active against susceptible gram-negative bacteria. Also provided is a purified, isolated DNA sequence encoding human bactericidal/permeability-increasing protein and biologically-active fragments thereof.
Inventors:
Elsback, Peter
Wais, gerold
Wais, gerold
Application Number:
JP33127899A
Publication Date:
September 11, 2000
Filing Date:
November 22, 1999
Export Citation:
Assignee:
New York University
International Classes:
C12N15/09; A61K38/00; A61K38/17; A61P31/04; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; (IPC1-7): C12N15/09; A61K38/00; A61P31/04; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Yoshihiro Tsunoda