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Title:
非浸出性または拡散性の酸化還元媒介剤を用いた小体積生体外分析物センサー
Document Type and Number:
Japanese Patent JP3553884
Kind Code:
B2
Abstract:
A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.

Inventors:
Feldman, Benjamin, Jay.
Heller, Adam
Heller, Eframe
Mao, Faye
Vivoro, Joseph, A.
Founder Burke, Jeffrey, Ve.
Colman, Frederick, Sea.
Krishnan, Rajesh
Application Number:
JP2000574718A
Publication Date:
August 11, 2004
Filing Date:
October 08, 1999
Export Citation:
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Assignee:
Cerasense, ink.
International Classes:
C12Q1/00; C12Q1/26; G01N27/327; G01N27/416; G01N27/42; G01N33/66; G01N33/483; (IPC1-7): G01N27/327; G01N27/416; G01N27/42; G01N33/483; G01N33/66
Domestic Patent References:
JP9264870U
JP8285814U
JP8320304U
JP6109688U
Foreign References:
WO1998035225A1
Attorney, Agent or Firm:
Hiroyuki Ikeuchi
Kimihiro Sato
Koichi Kamata
Keiji