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Title:
環式アミノ酸または環式ヒドロキシ酸誘導体により置換されたベンズアミジン誘導体および抗擬固薬としてのこれらの使用
Document Type and Number:
Japanese Patent JP3565864
Kind Code:
B2
Abstract:
This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.

Inventors:
Monica cochany
Michael M Morrissey
Howard peen
Application Number:
JP51325798A
Publication Date:
September 15, 2004
Filing Date:
September 11, 1997
Export Citation:
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Assignee:
Schering Aktiengesellschaft
International Classes:
A61K31/4439; A61K31/4725; A61K31/497; A61P7/02; C07D401/12; C07D401/14; C07D417/14; (IPC1-7): C07D401/12; A61K31/4439; A61K31/4725; A61K31/497; A61P7/02; C07D401/14; C07D417/14
Domestic Patent References:
JP2000515846A
Other References:
J.Med.Chem.,(1976),19(5),p.634-9
Thrombosis et Diathesis Haemorrhagica,(1975),33(2),p.230-243
Indian J.Experimental Biology,(1993),31(2),p.196-8
Thrombosis Res.,(1980),19(3),p.339-49
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard