Title:
ヒト悪性腫瘍の診断および治療の基礎としてのE-カドヘリンの突然変異体
Document Type and Number:
Japanese Patent JP3623342
Kind Code:
B2
Abstract:
The present invention describes monoclonal antibodies which are useful for the specific detection of diffuse gastric carcinoma. Further embodiments describe therapeutic and diagnostic means for the detection and for the therapy of diffuse gastric carcinomas.
Inventors:
Heinz Hofler
Karl-Friedrich Becker
Elizabeth Clemmer
Manfred Eulitz
Christoph Schumacher
Karl-Friedrich Becker
Elizabeth Clemmer
Manfred Eulitz
Christoph Schumacher
Application Number:
JP21406797A
Publication Date:
February 23, 2005
Filing Date:
July 24, 1997
Export Citation:
Assignee:
GS Forssungszentrum Fuer Umberto und Ges und Heit Gaem Behr
International Classes:
A01K67/027; A61K39/395; A61K47/48; A61K48/00; A61P35/00; C07K1/06; C07K14/705; C07K16/28; C07K16/30; C12N5/10; C12N5/20; C12N15/02; C12N15/12; C12P21/08; C12Q1/68; G01N33/574; G01N33/577; A61K38/00; C12R1/91; (IPC1-7): C07K16/30; A61K39/395; A61P35/00; C12N5/10; G01N33/574; G01N33/577
Domestic Patent References:
| JP7500723A |
Foreign References:
| WO1994011401A1 |
Other References:
Cancer Research,54[14](1994) p.3845-3852
Proc.Natl.Acad.Sci.USA,91(1994) p.1858-1862
Journal of the National Cancer Institute,87[14](19
Human Molecular Genetics,2[6](1993) p.803-804
Cancer Research,53[14](1993) p.3241-3245
Human Genetics,96[6](1995)p.739-740
Am.J.Patol.,155[6](1999) p.1803-1809
Proc.Natl.Acad.Sci.USA,91(1994) p.1858-1862
Journal of the National Cancer Institute,87[14](19
Human Molecular Genetics,2[6](1993) p.803-804
Cancer Research,53[14](1993) p.3241-3245
Human Genetics,96[6](1995)p.739-740
Am.J.Patol.,155[6](1999) p.1803-1809
Attorney, Agent or Firm:
Masatake Shiga