Title:
受容体Tieを認識するモノクローナル抗体およびそれらの用途
Document Type and Number:
Japanese Patent JP3683270
Kind Code:
B2
Abstract:
The present invention relates to an anti-Tie monoclonal antibody, 3C4C7G6, which is useful as a diagnostic tool for detecting angiogenesis-associated with neoplasia, wound healing, and a variety of other angiogenesis associated diseases and for radiological imaging of blood vessels. In addition, the disclosed antibody is useful as a therapeutic agent.
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Inventors:
Alitaro, Cali
Matikainen, Maruya-Terz
Karnani, Paevi
Matikainen, Maruya-Terz
Karnani, Paevi
Application Number:
JP52498895A
Publication Date:
August 17, 2005
Filing Date:
March 29, 1995
Export Citation:
Assignee:
Liscentia limited
International Classes:
A61K39/395; A61P35/00; A61P35/02; A61P43/00; C07K14/71; C07K16/28; C07K16/40; C12N5/00; C12N5/10; C12N5/20; C12N15/02; C12P21/08; G01N33/50; G01N33/534; G01N33/573; G01N33/574; G01N33/577; A61K38/00; C12R1/91; (IPC1-7): C12N15/02; C07K16/40; C12N5/10; G01N33/50; G01N33/534; G01N33/573; G01N33/574; G01N33/577
Foreign References:
| WO1993014124A1 |
Other References:
Molecular and Cellular Biology, 1992年,Vol.23, No.4, p.1698-1707
Attorney, Agent or Firm:
Sota Asahina
Kei Saki
Fumio Akiyama
Hiromu Tanaka
Kei Saki
Fumio Akiyama
Hiromu Tanaka