Title:
HIV逆転写酵素阻害剤としてのピラゾール誘導体
Document Type and Number:
Japanese Patent JP4088249
Kind Code:
B2
Abstract:
The invention is concerned with novel pyrazole derivatives, a process for their manufacture, pharmaceutical compositions and the use of such compounds in medicine. In particular, the compounds of formula I are inhibitors of the human immunodeficiency virus reverse transcriptase enzyme which is involved in viral replication. Consequently the compounds of this invention may be advantageously used as therapeutic agents for HIV mediated process.
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Inventors:
Brian William, Dymock
Gil, Adrian Liam
Jones, Philip Stephen
Parkes, Kevin Edward Burdon
Martin, John
Gil, Adrian Liam
Jones, Philip Stephen
Parkes, Kevin Edward Burdon
Martin, John
Application Number:
JP2003503620A
Publication Date:
May 21, 2008
Filing Date:
May 29, 2002
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D231/18; A61K31/415; A61K31/4155; A61K31/4439; A61K31/506; A61P31/18; C07D401/06; C07D401/12; C07D403/06; C07D405/12; C07D409/06
Domestic Patent References:
| JP2004511469A |
Foreign References:
| WO1996010019A1 |
Other References:
J Med Chem,2000年,Vol.43, No.5,1034-1040
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda