Title:
経口投与用時限放出型粒子状医薬組成物及び該組成物を含有する口腔内速崩壊錠
Document Type and Number:
Japanese Patent JP4277904
Kind Code:
B2
Abstract:
The present invention relates to an oral pharmaceutical composition in particle form, which comprises particles that contain a drug at the core of the pharmaceutical composition in particle form; a middle layer that contains two types of water-soluble components, an insolubilizer and an insolubilizing substance; and an outer layer for controlling water penetration that contains a water-insoluble substance. The present invention makes it possible to provide a pharmaceutical composition in particle form for oral use with which initial drug release is suppressed, the drug is quickly released thereafter, and lag time can be controlled as needed, and fast-disintegrating tablets containing this composition.
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Inventors:
Takayuki Yoshida
Hiroo Tasaki
Masataka Katsuma
Atsushi Maeda
Hiroo Tasaki
Masataka Katsuma
Atsushi Maeda
Application Number:
JP2006512834A
Publication Date:
June 10, 2009
Filing Date:
April 28, 2005
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
A61K9/16; A61K9/00; A61K9/20; A61K9/26; A61K9/50; A61K31/135; A61K31/439; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/24; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/40; A61K47/42; A61P1/04; A61P1/08; A61P3/02; A61P3/06; A61P3/10; A61P5/00; A61P5/38; A61P9/00; A61P9/04; A61P9/06; A61P9/08; A61P9/12; A61P11/10; A61P13/02; A61P19/10; A61P21/02; A61P23/02; A61P25/00; A61P25/02; A61P25/06; A61P25/08; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P29/00; A61P31/04; A61P35/00
Domestic Patent References:
| JP5194225A |
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke