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Title:
浸透圧デリバリーシステムの最小服従型で、容積効率型ピストン
Document Type and Number:
Japanese Patent JP4485945
Kind Code:
B2
Abstract:
An osmotic pump having a minimally compliant, volume-efficient piston positioned within a capsule is provided. The capsule has an interior surface, a beneficial agent, and an osmotic agent. The piston is movable with respect to an interior surface of the capsule, and defines a movable seal with the interior surface of the capsule. The movable seal separates the osmotic agent from the beneficial agent. The piston has a length-to-total-diameter ratio of about 1.1:1 and a core-diameter-to-total-diameter ratio of about 0.9:1. The piston enables greater beneficial agent and/or osmotic agent payload without increasing the size of the capsule. The osmotic agent imbibes liquid from a surrounding environment through a semipermeable body to cause the piston to move and, in turn, cause delivery of the beneficial agent from the capsule.

Inventors:
Rotenbach, Scott Dee
Application Number:
JP2004517856A
Publication Date:
June 23, 2010
Filing Date:
June 25, 2003
Export Citation:
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Assignee:
Intersia Therapeutics, Incorporated
International Classes:
A61M31/00; A61K9/00; A61K9/22; A61M5/145
Domestic Patent References:
JP2001510791A
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima
Nagasaka Tomoyasu
Yoshihiro Kobayashi
Satoshi Deno
Shintaro Koike
Jun Tsuruta
Tetsuro Shimada
Niwa Masataka
Hirose Shigeki
Yoshimitsu Mizumoto