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Title:
皮膚または皮膚付属物の色素沈着を刺激するための15-ヒドロキシプロスタグランジンデヒドロゲナーゼの阻害剤の使用
Document Type and Number:
Japanese Patent JP4584908
Kind Code:
B2
Abstract:
Inhibitors of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), for example tetrazole, styrylpyrazole, phenylfuran, phenylthiophene, phenylpyrrazole, pyrazolecarboxamide, 2-thioacetamide and azo compounds, are useful for promoting or stimulating pigmentation of the skin and/or skin appendages and/or for preventing and/or for limiting depigmentation and/or whitening of the skin and/or skin appendages, notably for preventing and/or limiting canities.

Inventors:
Jean-Francois Michele
Stephan com
Application Number:
JP2006500159A
Publication Date:
November 24, 2010
Filing Date:
February 12, 2004
Export Citation:
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Assignee:
LOREAL
International Classes:
A61K8/49; A61K8/06; A61K8/11; A61K8/36; A61K8/44; A61K9/113; A61K9/48; A61K9/51; A61K31/415; A61K31/4166; A61K31/427; A61K31/505; A61K31/517; A61K31/557; A61K45/00; A61P17/00; A61P43/00; A61Q1/10; A61Q5/00; A61Q5/10; A61Q19/04
Domestic Patent References:
JP62500872A
JP9504421A
Other References:
TAI,H.H. et al,Prostaglandin catabolizing enzymes,Prostaglandins Other Lipid Mediat,2002年,Vol.68-69,p.483-93
CAMP,R. et al,The catabolism of prostaglandins by rat skin,Biochemical Journal,1980年,Vol.186, No.1,p.153-60
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro