Title:
PPAR活性化剤としてのピラゾリルインドリル誘導体
Document Type and Number:
Japanese Patent JP4599395
Kind Code:
B2
Abstract:
This invention relates to compounds of the formula I: wherein one of R6, R7 and R8 is and R1 to R15 and n are as defined in the description, and all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR delta and/or PPARalpha agonists.
Inventors:
Ackerman, Jean
Shrimp, Johannes
Bingeri, Alfred
Greetter, uwe
Iltu, Georges
Kuhn, Bernd
Melchi, Hans-Peter
Marx, Meyer
Mall, peter
Light, matthew break
Shrimp, Johannes
Bingeri, Alfred
Greetter, uwe
Iltu, Georges
Kuhn, Bernd
Melchi, Hans-Peter
Marx, Meyer
Mall, peter
Light, matthew break
Application Number:
JP2007502232A
Publication Date:
December 15, 2010
Filing Date:
February 28, 2005
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D403/12; A61K31/4155; A61P1/04; A61P1/16; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P7/02; A61P9/10; A61P9/12; A61P15/00; A61P17/00; A61P17/06; A61P19/02; A61P25/28; A61P29/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP2000507216A |
Foreign References:
| WO2003074051A1 | ||||
| WO2003018553A1 | ||||
| WO2003099793A1 | ||||
| US20030225158 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda