Title:
リポソーム
Document Type and Number:
Japanese Patent JP4629308
Kind Code:
B2
Abstract:
Liposomes of a specific bilayer composition containing an entrapped modifying compound are claimed. The liposomes of the invention are suitable for the internalisation of a variety of materials, even following long-term storage. Suitable materials of the invention include radiometals, parmagnetic compounds, radioopaque compounds and prodrugs. Upon internalisation, the material reacts chemically with the entrapped modifying compound such that said material remains internalised within the liposomes of the invention. Also claimed in the present invention are the liposomes containing internalised material and kits for their preparation. Furthermore, the use of said liposomes containing internalised material for the imaging infection, inflammation or tumour in a human is claimed.
Inventors:
Sigrid Fosheim
Liv Ingrid Odegard Stuen
Liv Ingrid Odegard Stuen
Application Number:
JP2002586908A
Publication Date:
February 09, 2011
Filing Date:
May 10, 2002
Export Citation:
Assignee:
GE Healthcare Aksuye Sersukapu
International Classes:
A61K9/127; A61K47/18; A61K47/20; A61K47/24; A61K47/26; A61K47/28; A61K49/00; A61K49/04; A61K51/00; A61K51/12; A61P43/00; A61K47/22
Domestic Patent References:
| JP11171772A |
Foreign References:
| US5143713 | ||||
| WO2001003669A1 |
Attorney, Agent or Firm:
Arakawa Satoshi
Hirokazu Ogura
Toshihisa Kurokawa
Hirokazu Ogura
Toshihisa Kurokawa