Title:
M期キネシン阻害剤
Document Type and Number:
Japanese Patent JP4676881
Kind Code:
B2
Abstract:
A mitotic kinesin Eg5 inhibitor which comprises a thiadiazoline derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient:
[wherein R 1 represents a hydrogen atom and the like, R 2 represents a hydrogen atom, -C(=W)R 6 (wherein W represents an oxygen atom or a sulfur atom, and R 6 represents substituted or unsubstituted lower alkyl and the like) and the like, R 3 represents -C(=Z)R 19 (wherein Z represents an oxygen atom or a sulfur atom, and R 19 represents substituted or unsubstituted lower alkyl and the like) and the like, R 4 represents substituted or unsubstituted lower alkyl and the like, and R 5 represents substituted or unsubstituted aryl and the like] and the like are provided.
Inventors:
Muragata power
Yamashita Jun
Ryuichiro Nakai
Akasaka alone
Yoji Ino
Kazuhiko Kato
Takeshi Kitamura
Yamashita Jun
Ryuichiro Nakai
Akasaka alone
Yoji Ino
Kazuhiko Kato
Takeshi Kitamura
Application Number:
JP2005505480A
Publication Date:
April 27, 2011
Filing Date:
April 16, 2004
Export Citation:
Assignee:
Kyowa Hakko Kirin Co., Ltd.
FUJIFILM Corporation
FUJIFILM Corporation
International Classes:
C07D285/12; A61K31/433; A61K31/4439; A61K31/506; A61K31/5377; A61P9/00; A61P9/04; A61P9/10; A61P19/02; A61P37/00; A61P37/02; A61P43/00; C07D285/13; C07D285/135
Domestic Patent References:
| JP2003048881A | 2003-02-21 | |||
| JP4272994B2 | 2009-06-03 |
Foreign References:
| WO2003079973A2 | 2003-10-02 | |||
| WO2003103575A2 | 2003-12-18 |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes