Title:
温度感受性リポソーム製剤
Document Type and Number:
Japanese Patent JP4691253
Kind Code:
B2
Abstract:
Temperature sensitive liposomes containing active agents are described. The liposomes comprise phospholipids and a surface active agent, such as a lysolipid, that increases the amount of active agent released by the liposome at the phase transition temperature of the liposome. Such liposomes are useful in methods of administering active agents using mild hyperthermic conditions.
Inventors:
David, Needham
Application Number:
JP2000554346A
Publication Date:
June 01, 2011
Filing Date:
June 09, 1999
Export Citation:
Assignee:
Duke University
International Classes:
A61K9/127; A61K31/192; A61K31/337; A61K31/437; A61K31/4745; A61K31/517; A61K31/573; A61K31/704; A61K33/24; A61K45/00; A61K47/24; A61K47/34; A61P29/00; A61P31/04; A61P35/00; A61P37/06
Domestic Patent References:
| JP5000239A | ||||
| JP5506670A | ||||
| JP5508626A |
Other References:
Macromolecules,1995年,28,7693-7699
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Naomi Yoshida
Ayako Nakamura
Fukagawa Eri
Satoshi Morimoto
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Naomi Yoshida
Ayako Nakamura
Fukagawa Eri
Satoshi Morimoto
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