Title:
C8連結したピロロ[2,1-c][1,4]ベンゾジアゼピン-アクリドン/アクリジン・ハイブリッド
Document Type and Number:
Japanese Patent JP4718328
Kind Code:
B2
Abstract:
The present invention provides novel pyrrolo-[2,1-c][1,4]benzodiazepine of the formula given below wherein R is Hor OH and n is 2-3 (formula (I) and (II) useful as and-tumour agents and a process for the preparation thereof.
Inventors:
Kamal, Ahmed
Srinivas, Olep
Lamuru, Poddutori
Ramesh, Gujar
Praven Kumar, Pogra
Srinivas, Olep
Lamuru, Poddutori
Ramesh, Gujar
Praven Kumar, Pogra
Application Number:
JP2005512763A
Publication Date:
July 06, 2011
Filing Date:
December 31, 2003
Export Citation:
Assignee:
Council of Scientific and Industrial Research
International Classes:
C07D487/04; A61K31/5517; A61P35/00; A61P35/02
Domestic Patent References:
| JP59007171A | ||||
| JP2001503399A |
Other References:
SCHOFIELD P C,CANCER CHEMOTHERAPY AND PHARMACOLOGY,ドイツ,SPRINGER VERLAG,,1999年 7月,V44 N1,P51-58
KAMAL A,CURRENT MEDICINAL CHEMISTRY.ANTI-CANCER AGENTS,NL,2002年,V2 N2,P215-254
KAMAL AHMED,BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS,2002年 8月 5日,V12 N15,P1933-1935
KAMAL A,JOURNAL OF MEDICINAL CHEMISTRY,米国,AMERICAN CHEMICAL SOCIETY,2002年,V45,P4679-4688
Palmer,B.D.,et al,Journal of Medicinal Chemistry,1988年,Vol.31,pages 707-712
GAMAGE A W,TETRAHEDRON LETTERS,,NL,ELSEVIER SCIENCE PUBLISHERS,1997年 1月27日,V38 N4,P699-702
KAMAL A,CURRENT MEDICINAL CHEMISTRY.ANTI-CANCER AGENTS,NL,2002年,V2 N2,P215-254
KAMAL AHMED,BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS,2002年 8月 5日,V12 N15,P1933-1935
KAMAL A,JOURNAL OF MEDICINAL CHEMISTRY,米国,AMERICAN CHEMICAL SOCIETY,2002年,V45,P4679-4688
Palmer,B.D.,et al,Journal of Medicinal Chemistry,1988年,Vol.31,pages 707-712
GAMAGE A W,TETRAHEDRON LETTERS,,NL,ELSEVIER SCIENCE PUBLISHERS,1997年 1月27日,V38 N4,P699-702
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura