Title:
第四級化アンモニウムシクロデキストリン化合物
Document Type and Number:
Japanese Patent JP4773721
Kind Code:
B2
Abstract:
Use of a compound of formula (I): wherein the symbol cyclodextrin ]n represents a n-valent residue derived from a cyclodextrin compound by removing n of its hydroxyl groups; n is a number greater than 0 and represents the average number of substituents of formula per molecule of said compound; h is 0 or 1; R1 is a di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene, monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are each independently of one another a group selected from alkyl, cycloalkyl, aryl, aralkyl, and cycloheteryl; Xm- is a m-fold negatively charged anion; m is an integer being equal or greater than 1; and k is n/m in the preparation of an anti-infective medicament, as preservative and penetration enhancer.
Inventors:
Georg Ludwig Kiss
Christian schoch
Youjeff Seitori
Christian schoch
Youjeff Seitori
Application Number:
JP2004512769A
Publication Date:
September 14, 2011
Filing Date:
June 12, 2003
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/724; A61K47/30; A61K45/00; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/40; A61P17/00; A61P27/02; A61P31/00; A61P31/04; C08B37/16
Domestic Patent References:
| JPH0665307A | 1994-03-08 | |||
| JPH02272001A | 1990-11-06 | |||
| JPS58210901A | 1983-12-08 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima