Title:
動脈閉塞性疾病モデル動物の作製
Document Type and Number:
Japanese Patent JP4779122
Kind Code:
B2
Abstract:
The present invention relates to a method for generating a non-human model animal of an arterial occlusive disease, wherein the method is characterized in that an artery is occluded at a specific site by ligating it or with an autologous blood clot. In particular, the present invention relates to a method and a kit for generating a cardiac infarction model, as well as a cardiac infarction animal model obtained by employing the method or kit, characterized in that in a non-human experimental animal, a blood vessel is ligated downstream of an arterial site of the heart to be occluded, followed by occluding the artery at said site. In addition, the present invention also relates to a method and a system for generating a non-human animal model of arterial embolus, as well as an arterial embolus animal model obtained by employing the method or system, characterized by adding an coagulating agent to autologous blood to form an autologous blood clot and subsequently employing an angiographic apparatus in delivering the autologous blood clot into an artery.
Inventors:
Hidehiro Iida
Yoichiro Ota
Teramoto Noboru
Takuya Hayashi
Yoichiro Ota
Teramoto Noboru
Takuya Hayashi
Application Number:
JP2006535873A
Publication Date:
September 28, 2011
Filing Date:
September 12, 2005
Export Citation:
Assignee:
Human Science Promotion Foundation
International Classes:
A01K67/027
Other References:
上原記念生命科学財団研究報告集, (2003), 17, p.352-356
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita