Title:
肝線維化抑制剤
Document Type and Number:
Japanese Patent JP4822291
Kind Code:
B2
Inventors:
Yoichiro Takami
Hirohito Tsubouchi
Hirofumi Utsu
Hiroaki Kataoka
Masahiko Takeshita
Hirohito Tsubouchi
Hirofumi Utsu
Hiroaki Kataoka
Masahiko Takeshita
Application Number:
JP2008318593A
Publication Date:
November 24, 2011
Filing Date:
December 15, 2008
Export Citation:
Assignee:
Miyazaki Prefecture Industrial Support Foundation
National University Corporation Kagoshima University
National University Corporation Miyazaki University
Southern Japan Dairy Co., Ltd.
National University Corporation Kagoshima University
National University Corporation Miyazaki University
Southern Japan Dairy Co., Ltd.
International Classes:
A61K31/353; A61P1/16; A61P43/00; A23L1/30; A23L2/52; C07D311/62
Domestic Patent References:
| JP2007119398A | ||||
| JP2007320958A | ||||
| JP2007519752A |
Foreign References:
| WO2005030200A1 |
Other References:
Fukuchi, K., et al.,"Inhibition of herpes simplex virus infection by tannins and related compounds",Antiviral Research,1989年,vol.11,pp.285-298
Sakata, R., et al.,"Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90",Journal of Hepatology,2004年,vol.40, no.1,pp.52-59
Chen, A., et al.,"The Antioxidant (-)-Epigallocatechin-3-gallate Inhibits Rat Hepatic Stellate Cell Proliferation in Vitro by Blocking the Tyrosine Phosphorylation and Reducing the Gene Expression of Platelet-derived Growth Factor-β Receptor",The Journal of Biological Chemistry,2003年,Vol.278, No.26,pp.23381-23389
Higashi, N., et al.,"Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells",Journal of Laboratory and Clinical Medicine,2005年,vol.145, no.6,pp.316-322
Sakata, R., et al.,"Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90",Journal of Hepatology,2004年,vol.40, no.1,pp.52-59
Chen, A., et al.,"The Antioxidant (-)-Epigallocatechin-3-gallate Inhibits Rat Hepatic Stellate Cell Proliferation in Vitro by Blocking the Tyrosine Phosphorylation and Reducing the Gene Expression of Platelet-derived Growth Factor-β Receptor",The Journal of Biological Chemistry,2003年,Vol.278, No.26,pp.23381-23389
Higashi, N., et al.,"Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells",Journal of Laboratory and Clinical Medicine,2005年,vol.145, no.6,pp.316-322
Attorney, Agent or Firm:
Yoshiki Hasegawa
Yoshinori Shimizu
Yoshinori Shimizu