Title:
抗増殖活性を有し、そして/または核酸損傷剤を増大するペプチドおよびペプチド模倣物あるいは処置
Document Type and Number:
Japanese Patent JP4873646
Kind Code:
B2
Abstract:
This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting G2 cell cycle checkpoint. Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.
Inventors:
Takumi Kawabe
Eitaka Kobayashi
Eitaka Kobayashi
Application Number:
JP2007218979A
Publication Date:
February 08, 2012
Filing Date:
August 24, 2007
Export Citation:
Assignee:
Canvas Co., Ltd.
International Classes:
A61K38/00; C07K7/02; A61K33/24; A61K38/55; A61K47/48; A61K51/08; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07K5/06; C07K5/065; C07K7/06; C07K7/08
Foreign References:
| WO2001021771A1 |
Other References:
Cancer Res.,1999年,Vol.59,p.5887-5891
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita