Title:
ストレプトミセスから得られたワクチン組成物
Document Type and Number:
Japanese Patent JP4875606
Kind Code:
B2
Abstract:
The present invention relates to the filed of immunology and, more specifically, to the control of infectious diseases caused by microbacteria, which is based on the use of vaccines for the prevention of said diseases. The inventive vaccines have been developed with the use of live strains of Streptomyces, which may or may not express antigens of M. tuberculosis, and have demonstrated their protective capacity against the threat of BCG and M. tuberculosis after being administered by different routes. The invention also relates to the use of strains of Streptomyces for the expression of heterologous antigens of vaccinal interest.
Inventors:
Sarmiento Garcia Sam Miguel, Maria, Elena
Acosta Dominguez, Armando
Ballin Prous, Carlos, Roman
Olivares Arsuaga, Nesti
Lopez Hernandez, Jamire
Rodriguez Valdes, Carida
Martinez Benitez, Maximo
Gonzalez Mesa, Leonora
Infante Bowl Sack, Fan, Francisco
Ramos Mori, Astori
Acosta Dominguez, Armando
Ballin Prous, Carlos, Roman
Olivares Arsuaga, Nesti
Lopez Hernandez, Jamire
Rodriguez Valdes, Carida
Martinez Benitez, Maximo
Gonzalez Mesa, Leonora
Infante Bowl Sack, Fan, Francisco
Ramos Mori, Astori
Application Number:
JP2007503180A
Publication Date:
February 15, 2012
Filing Date:
March 18, 2005
Export Citation:
Assignee:
Institute Finlay. Centro de Investigation-Producion de Bacuna Iseros
Centro de Quimica Farma Sutica
Centro de Quimica Farma Sutica
International Classes:
A61K39/02; A61K39/00; A61K39/04; A61P31/06
Domestic Patent References:
| JP6503802A |
Foreign References:
| WO1998044120A1 |
Other References:
TREMBLAY, D. et al.,Can. J. Microbiol.,2002年,Vol.48,pp.43-48
CRAWFORD, C.R. et al.,Clin. Exp. Immunol.,1982年,Vol.48,pp.739-746
CRAWFORD, C.R. et al.,Clin. Exp. Immunol.,1982年,Vol.48,pp.739-746
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda