Title:
特異的または選択的α2アドレナリン作動剤としての不置換および置換4-ベンジル-1,3-ジヒドロ-イミダゾール-2-チオンならびにその使用方法
Document Type and Number:
Japanese Patent JP4986856
Kind Code:
B2
Abstract:
Compounds of Formula 1 where the variables have the meaning defined in the specification are used to activate alpha2 adrenergic receptors. The compounds of Formula 1 are incorporated in pharmaceutical compositions and are used as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2 adrenergic receptors.
Inventors:
Todd M Heidelbo
Ken Chow
Von X Nguyen
Daniel W. Gill
John E. Donello
Michael E. Gurst
Larry A Wheeler
John Earl Cappiello
Ken Chow
Von X Nguyen
Daniel W. Gill
John E. Donello
Michael E. Gurst
Larry A Wheeler
John Earl Cappiello
Application Number:
JP2007534620A
Publication Date:
July 25, 2012
Filing Date:
September 07, 2005
Export Citation:
Assignee:
ALLERGAN,INCORPORATED
International Classes:
C07D233/84; A61K31/4166; A61P25/00; A61P25/04; A61P29/02
Domestic Patent References:
| JP64029365A | ||||
| JP59205366A | ||||
| JP2001524542A | ||||
| JP2004528313A |
Foreign References:
| WO2003099795A1 | ||||
| WO2003048130A1 | ||||
| WO2002036162A1 | ||||
| WO2003099289A1 |
Other References:
Sadao Maeda et al.,Chem. Pharm. Bull.,1984年,Vol.32(7),p.2536-2543
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Kyousei Tamura
Yasuo Shibata
Nagatoshi Shinagawa
Takuji Yamada
Kyousei Tamura
Yasuo Shibata
Nagatoshi Shinagawa