Title:
根管充填材
Document Type and Number:
Japanese Patent JP5621105
Kind Code:
B2
Abstract:
Provided is a novel and creative dental tissue regeneration method for regenerating dental tissue after pulpectomy or the enlargement and cleaning of an infected root canal. After pulpectomy or the enlargement and cleaning of an infected root canal, a root canal filler (200) having an extracellular matrix (210) containing the cells (220) enriched for dental pulp stem cells , is inserted into the apical side of the root canal of a target tooth (100). The cells including dental pulp stem cells include at least one of the following: dental pulp SP cells, CD31-neative and CD146-negative cells, CD24-positive cells, CD105-positive cells, and CD150-positive cells. For instance, dental pulp SP cells are CD31- and CD146- negative. Even if pulpitis due to deep caries occurs, appropriate dental pulp regeneration and recovery of dental pulp function are possible.
Inventors:
中島 美砂子
庵原 耕一郎
庵原 耕一郎
Application Number:
JP2010502914A
Publication Date:
November 05, 2014
Filing Date:
March 12, 2009
Export Citation:
Assignee:
公益財団法人ヒューマンサイエンス振興財団
International Classes:
A61L27/00; A61C5/02
Other References:
JPN6013039967; 平成１８年度 政策創薬総合研究事業 若手研究者奨励研究報告書 , 20070731, Ｐ．１６２-１６６
JPN6014031033; ＭＥＤＩＣＡＬ ＡＮＤ ＣＬＩＮＩＣＡＬ ＡＳＰＥＣＴＳ ＶＯＬ．３, 2007, Ｐ．２６５-２８１
JPN6014031035; ＢＩＯＭＡＴＥＲＩＡＬＳ ＶＯＬ．２７, 2006, Ｐ．５６５８-５６６８
JPN6009029994; 中川寛一ら: 'ハイドロキシアパタイトの根管充填材としての応用価値に関する実験病理学的研究（第１報）' 日歯保誌 第２７巻、第１号, 1984, ｐ．１９０-１９９
JPN6014031033; ＭＥＤＩＣＡＬ ＡＮＤ ＣＬＩＮＩＣＡＬ ＡＳＰＥＣＴＳ ＶＯＬ．３, 2007, Ｐ．２６５-２８１
JPN6014031035; ＢＩＯＭＡＴＥＲＩＡＬＳ ＶＯＬ．２７, 2006, Ｐ．５６５８-５６６８
JPN6009029994; 中川寛一ら: 'ハイドロキシアパタイトの根管充填材としての応用価値に関する実験病理学的研究（第１報）' 日歯保誌 第２７巻、第１号, 1984, ｐ．１９０-１９９
Attorney, Agent or Firm:
Patent business corporation MAEDA PATENT OFFICE
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