Title:
核酸検出用キット
Document Type and Number:
Japanese Patent JP5704481
Kind Code:
B2
Abstract:
To provide a nucleic acid detecting kit, capable of easily and high-sensitively detecting a target nucleic acid.
The nucleic acid detecting kit includes an enzyme substrate modification nucleoside triphosphate shown in Equation 1. In Equation 1, A is a substitution group containing at least one of an alkyl group, an aminoalkyl group, an aryl group, and a heteroaryl group with linear, branched, or annular saturation, or unsaturation having a glutamine (Gln) residue or a lysine (Lys) residue, or a primary amine, and B is a hydrogen atom or a hydroxyl group.
COPYRIGHT: (C)2011,JPO&INPIT
Inventors:
Noriho Kamiya
Kitaoka Momoko
Yukari Tanaka
Onoe Kadai
Noharu Sumiharu
Hiroyuki Hayashi
Masayuki Mitsumori
Yusuke Tomoe
Kitaoka Momoko
Yukari Tanaka
Onoe Kadai
Noharu Sumiharu
Hiroyuki Hayashi
Masayuki Mitsumori
Yusuke Tomoe
Application Number:
JP2010049631A
Publication Date:
April 22, 2015
Filing Date:
March 05, 2010
Export Citation:
Assignee:
Kyushu University
Tokushima University
Hitachi Aloka Medical Co., Ltd.
Tokushima University
Hitachi Aloka Medical Co., Ltd.
International Classes:
C12Q1/68; C12Q1/48; G01N33/53; G01N33/533; G01N33/534; G01N33/535
Domestic Patent References:
| JP2008054658A | ||||
| JP2001288197A | ||||
| JP2001525797A | ||||
| JP2001519354A | ||||
| JP2004532184A | ||||
| JP2004529650A | ||||
| JP2002507203A | ||||
| JP2000504009A | ||||
| JP5146785B2 | ||||
| JP4621926B2 | ||||
| JP1101900A | ||||
| JP8089278A | ||||
| JP2000300287A |
Other References:
STUHMILLER et al,Advances in Enzyme Regulation,1989年,Vol.29,p.141-157
Kuwahara et al,Bioorganic & Medicinal Chemistry,2006年,Vol.14,p.2518-2526
Kuwahara et al,Nucleic Acids Research Supplement,2002年,Vol.2,p.83-84
神谷典穂、外2名,酵素反応による生体分子ラベル化に適した新規蛍光基質のデザイン,化学工学会九州支部大会研究発表講演要旨集,2008年 8月,A107
Mindt et al,Bioconjugate Chem.,2008年,Vol. 19,p. 271-278
Kuwahara et al,Bioorganic & Medicinal Chemistry,2006年,Vol.14,p.2518-2526
Kuwahara et al,Nucleic Acids Research Supplement,2002年,Vol.2,p.83-84
神谷典穂、外2名,酵素反応による生体分子ラベル化に適した新規蛍光基質のデザイン,化学工学会九州支部大会研究発表講演要旨集,2008年 8月,A107
Mindt et al,Bioconjugate Chem.,2008年,Vol. 19,p. 271-278
Attorney, Agent or Firm:
Kenji Yoshida
Jun Ishida
Jun Ishida