インテグラーゼ阻害活性を有するピリドン誘導体

Japanese Patent JP5766690

B2

An object of the present invention is to provide a novel integrase inhibitor. The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses, in particular, HIV and drug-resistant strains thereof. Thus, the compound is useful in preventing or treating various diseases, viral infections (for example, AIDS), and the like in which integrase participates.

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Hattori Kazunari
Kenji Tomita

JP2012510566A

August 19, 2015

April 11, 2011

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Shionogi Pharmaceutical Co., Ltd.

C07D471/04; A61K31/53; A61K31/5365; A61K31/5377; A61P31/18; A61P43/00; C07D498/14; C07D519/00

JP2008540343A

2008-11-20

WO2005016927A1	2005-02-24
WO2007049675A1	2007-05-03
WO2006030807A1	2006-03-23

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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