Title:
食欲を調節する方法
Document Type and Number:
Japanese Patent JP5767667
Kind Code:
B2
Abstract:
The present invention provides a method of modulating appetite and/or body weight in a subject, said method comprising administering to said subject an effective amount of a MIC-1-modulating agent, wherein said agent increases or decreases the amount of MIC-1 present in said subject, or inhibits or enhances the biological activity of MIC-1 present in said subject.
Inventors:
Blait Samuel Norbert
Bowskin Asne Rhoda
Bowskin Asne Rhoda
Application Number:
JP2013086022A
Publication Date:
August 19, 2015
Filing Date:
April 16, 2013
Export Citation:
Assignee:
St Vincents Hospital Sydney Limited
International Classes:
A61K39/395; A61K38/00; A61K38/19; A61P1/14; A61P3/00; A61P3/04; A61P43/00; C07K16/22; G01N33/53; G01N33/68
Other References:
Cancer Research,2003年,Vol.63,No.16,p5034-5040
Fairlie WD et al.,MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation,Journal of Leukocyte Biology,1999年 1月,Vol.65,pp.2-5
Zereu M et al.,p53 and bcl-2 protein expression and its relationship with prognosis in the patients with small cell,Proc Am Soc Clin Oncol,2002年,Vol.22,No.1343
Fairlie WD et al.,MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation,Journal of Leukocyte Biology,1999年 1月,Vol.65,pp.2-5
Zereu M et al.,p53 and bcl-2 protein expression and its relationship with prognosis in the patients with small cell,Proc Am Soc Clin Oncol,2002年,Vol.22,No.1343
Attorney, Agent or Firm:
Masaki Hirota