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Title:
肝機能障害予防剤
Document Type and Number:
Japanese Patent JP5823695
Kind Code:
B2
Abstract:
Disclosed is a prophylactic agent for hepatic function disorders, of which the clinical efficacy has been confirmed, and which has high safety and is free from the concerns about adverse side effects.  The prophylactic agent comprises kefir as an active ingredient.

Inventors:
Tetsuji Okamoto
Ryoji Tani
Koichiro Tokumaru
Tokumaru Sennosuke
Application Number:
JP2010541239A
Publication Date:
November 25, 2015
Filing Date:
December 03, 2009
Export Citation:
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Assignee:
Hiroshima University
Japan Kefir Co., Ltd.
International Classes:
A61K35/74; A61K35/20; A61K36/06; A61P1/02; A61P1/16; A61P35/00
Domestic Patent References:
JPH0838046A1996-02-13
JPH11504936A1999-05-11
JPS61221124A1986-10-01
JP2007236227A2007-09-20
JP2006288243A2006-10-26
JP2008054628A2008-03-13
JP2004307514A2004-11-04
Other References:
JPN6009068321; 前田浩明: '米培地乳酸菌培養物「米ケフィラン」の特性と機能性食品への応用' 食品と開発 Vol.40 No.9, 20050901, pp.55-57
JPN6009068324; '牛乳消費を伸ばしたい*ヨーグルトキノコ使いオリジナルブランド*中標津' 北海道新聞朝刊全道 , 19940401, p.23
JPN6009068325; '日本ペプシ、ケフィア発酵乳入り乳性飲料「エクセリーナ・ケフォール」発売' 日本食糧新聞 , 19941021
JPN6009068328; '日本ケフィア、複合発酵乳飲料「コーカサスケフィア」発売' 日本食糧新聞 , 19940810
JPN6014007732; 寺田厚: 'ホームメイド・ケフィア摂取における腸内細菌叢および腐敗産物への効果' 有限会社中垣技術士事務所ホームページ , 20060716
JPN6014007733; El-kassaby I et al.: 'Comparative effects of milk and fermentd milk diets on the regeneration of the rat liver' Egypt. J. Pharm. Sci. Vol.38 No.4-6, 1997, pp.521-530
JPN6014007734; Powell JE et al.: 'Characterization of bacteriocin ST8KF produced by a kefir isolate Lactobacillus plantarum ST8KF' International Dairy Journal Vol.17 No.3, 200703, pp.190-198
JPN6014007735; Simova E et al.: 'Amino acid profiles of lactic acid bacteria, isolated from kefir grains and kefir starter made from' Int J Food Microbiol. Vol.107 No.2, 20051116, pp.112-123
JPN6014007736; Beshkova DM et al.: 'Pure cultures for making kefir' Food Microbiology Vol.19 No.5, 200210, pp.537-544
JPN6009068331; 添付文書(シスプラチン注10mg「日医工」) 第2版, 200701
Attorney, Agent or Firm:
Axis International Patent Business Corporation
Hiroyuki Koitabashi