Title:
ＨＥＣ１活性の調節因子およびそのための方法
Document Type and Number:
Japanese Patent JP5825535
Kind Code:
B2
Abstract:
Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Especially preferred compounds disrupt Nek2/Hec1 binding and are therefore useful as chemotherapeutic agent for neoplastic diseases.
Inventors:
Lau, Johnson
Fan, Jean-Gee
Fan, Jean-Gee
Application Number:
JP2013500159A
Publication Date:
December 02, 2015
Filing Date:
March 15, 2011
Export Citation:
Assignee:
TAIVEX THERAPEUTICS CORPORATION
International Classes:
C07D417/12; A61K31/4439; A61P35/00; A61P43/00
Domestic Patent References:
| JP2009503107A | ||||
| JP2007504255A | ||||
| JP2008509923A |
Foreign References:
| US20050113420 | ||||
| WO2008124000A1 | ||||
| US20060140956 | ||||
| WO2009140621A1 | ||||
| WO2007004038A1 |
Other References:
Journal of Medicinal Chemistry,2009年,Vol.52(6),p.1757-1767
Cancer Research,2008年,Vol.68(20),p.8393-8399
DATABASE PubChem [Online] NCBI, XP002699247, Database accession no. CID 2322088,2005年 7月15日,URL:https://pubchem.ncbi.nlm.nih.gov/compound/2322088?from=summary
DATABASE PubChem [Online] NCBI, XP002699248, Database accession no. CID 1554161,2005年 7月11日,URL:https://pubchem.ncbi.nlm.nih.gov/compound/1554161?from=summary
DATABASE PubChem [Online] NCBI, XP002699249, Database accession no. CID 1185425,2005年 7月10日,URL:https://pubchem.ncbi.nlm.nih.gov/compound/1185425?from=summary
INDIAN JOURNAL OF CHEMISTRY B,1986年,Vol.25B(12),p.1266-1268
Journal of the Institution of Chemists,1977年,Vol.49(6),p.294-296
Arzneimittel-Forschung,1984年,Vol.34(5),p.599-603
Cancer Research,2008年,Vol.68(20),p.8393-8399
DATABASE PubChem [Online] NCBI, XP002699247, Database accession no. CID 2322088,2005年 7月15日,URL:https://pubchem.ncbi.nlm.nih.gov/compound/2322088?from=summary
DATABASE PubChem [Online] NCBI, XP002699248, Database accession no. CID 1554161,2005年 7月11日,URL:https://pubchem.ncbi.nlm.nih.gov/compound/1554161?from=summary
DATABASE PubChem [Online] NCBI, XP002699249, Database accession no. CID 1185425,2005年 7月10日,URL:https://pubchem.ncbi.nlm.nih.gov/compound/1185425?from=summary
INDIAN JOURNAL OF CHEMISTRY B,1986年,Vol.25B(12),p.1266-1268
Journal of the Institution of Chemists,1977年,Vol.49(6),p.294-296
Arzneimittel-Forschung,1984年,Vol.34(5),p.599-603
Attorney, Agent or Firm:
Masaki Yamakawa
Shigeki Yamakawa
Shuichiro Kitamura
Ichiro Miyake
Takashi Ota
Shigeki Yamakawa
Shuichiro Kitamura
Ichiro Miyake
Takashi Ota
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