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Title:
ステロイドに対する応答性を調節する方法
Document Type and Number:
Japanese Patent JP5886699
Kind Code:
B2
Abstract:
The present invention makes it possible to enhance steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an effective to said patient amount of an oligonucleotide comprising the sequence TTCGT and having a total length of up to 100 nucleotides. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals.

Inventors:
Anne-Kristin Speak
Robert Lefberg
Lisa Charlotte Bandholtz
Oliver von Stain
Arezou Zargari
Application Number:
JP2012149039A
Publication Date:
March 16, 2016
Filing Date:
July 03, 2012
Export Citation:
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Assignee:
Index Pharmaceuticals Actie Borag
International Classes:
A61K31/7088; A61K31/57; A61K31/712; A61K31/7125; A61P1/04; A61P11/00; A61P11/06; A61P17/06; A61P19/02; A61P29/00; C12N15/117
Domestic Patent References:
JP5208734B2
JP2012232988A
JP2008535859A
JP2008544984A
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi



 
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