Title:
空間コード化生物学的アッセイ
Document Type and Number:
Japanese Patent JP5893607
Kind Code:
B2
Abstract:
Provided herein are methods of identifying a target protein in a tissue sample that include delivering a plurality of probes to a tissue sample, where a probe of the plurality of probes comprises an antibody conjugated to an oligonucleotide having a sequence, where the antibody specifically binds to the target protein in the tissue sample; amplifying the oligonucleotide to generate an amplicon comprising copies of the oligonucleotide; detecting all or a portion of a copy of the oligonucleotide in the amplicon; and using the detected sequence to identify the target protein in the tissue sample.
Inventors:
Chi, Mark S.
Application Number:
JP2013503861A
Publication Date:
March 23, 2016
Filing Date:
April 05, 2011
Export Citation:
Assignee:
PROGNOSYS BIOSCIENCES,INC.
International Classes:
C12Q1/68; C12N15/115; G01N33/53; G01N33/543; G01N37/00
Foreign References:
| US20060046313 | ||||
| WO2010019826A1 |
Other References:
Nucleic Acids Research,2009年,Vol.37, No.1, e5,doi:10.1093/nar/gkn906
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Atsushi Honda
Makoto Onda
Atsushi Honda