Title:
実質的な定常状態薬物送達の迅速な確立及び／又は停止
Document Type and Number:
Japanese Patent JP6517777
Kind Code:
B2
Abstract:
The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method typically includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is typically achieved within about 7 days or less after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using incretin mimetics.
Inventors:
Thomas Earl. Areci
Kennis El. Rusky
Kennis El. Rusky
Application Number:
JP2016237525A
Publication Date:
May 22, 2019
Filing Date:
December 07, 2016
Export Citation:
Assignee:
Intersia Therapeutics, Incorporated
International Classes:
A61K9/10; A61K38/17; A61K47/10; A61K47/14; A61K47/32; A61P1/08; A61P3/04; A61P3/06; A61P3/10; A61P9/12
Domestic Patent References:
| JP10502285A |
Foreign References:
| WO2008133908A1 | ||||
| WO2008021133A1 |
Other References:
ROHLOFF CATHERINE M ET AL,DUROS technology delivers peptides and proteins at consistent rate continuously for 3 to 12 months,JOURNAL OF DIABETES SCIENCE AND TECHNOLOGY,米国,DIABETES TECHNOLOGY SOCIETY,2008年 5月,vol. 2, no.3,pages 461-467
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei