Title:
遺伝子改変Ｔ細胞受容体マウス
Document Type and Number:
Japanese Patent JP6532924
Kind Code:
B2
Abstract:
The invention provides a genetically modified non-human animal that comprises in its genome unarranged T cell receptor gene loci, as well as non-human embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.
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Inventors:
Lynn McDonald
Andrew Jay Murphy
John Miku Wilter
Nakshin Two
Bella Boronina
Cagan regular
Carolina Meagher
Sean Stevens
Andrew Jay Murphy
John Miku Wilter
Nakshin Two
Bella Boronina
Cagan regular
Carolina Meagher
Sean Stevens
Application Number:
JP2017205098A
Publication Date:
June 19, 2019
Filing Date:
October 24, 2017
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
A01K67/027; C12N15/12; C12N15/62
Domestic Patent References:
| JP2005505236A |
Foreign References:
| WO2011004192A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita