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Title:
粒度分布が調節されたヒドロキシプロピルメチルセルロースアセテートサクシネート(HPMCAS)粒子の製造方法、及びHPMCAS粉末
Document Type and Number:
Japanese Patent JP6542767
Kind Code:
B2
Abstract:
Disclosed are a method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains and HPMCAS grains. The disclosed method for preparing HPMCAS grains comprises: a step of esterifying hydroxypropyl methylcellulose (HPMC), acetic anhydride, and succinic anhydride in a reaction medium in the presence of a catalyst so as to obtain a reaction solution containing HPMCAS (esterification step); and a step of continuously or intermittently putting the reaction solution into water so as to form grains (granulating step).

Inventors:
Sun Fan Bang
Ju Hee Shin
Jin Lul Song
Kyun Yeol Park
John Hee Chun
The Song Jung
San Job Lee
Application Number:
JP2016526073A
Publication Date:
July 10, 2019
Filing Date:
December 15, 2014
Export Citation:
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Assignee:
LOTTE Fine Chemical Co.,Ltd.
International Classes:
C08B13/00
Domestic Patent References:
JP2008501009A
JP2013532151A
JP4293901A
Foreign References:
WO2013148154A1
WO2013154607A1
Attorney, Agent or Firm:
Yasuhiko Murayama
Tatsuhiko Abe
Choi