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Title:
ピリジル−トリアザビシクル
Document Type and Number:
Japanese Patent JP6594403
Kind Code:
B2
Abstract:
having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.

Inventors:
Bartels, Bjorn
Drenthe, Cosimo
Gouva, Wolfgang
Harp, wolfgang
Kugle Stutter, Andreas
Opst Zander, Ulrike
Peters, Jens-Uwe
Rogers-Evans, Mark
Voltering, Thomas
Schneider, christian
Vermeut, Logaire
Application Number:
JP2017502976A
Publication Date:
October 23, 2019
Filing Date:
July 21, 2015
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D513/04; A61K31/554; A61P25/28
Domestic Patent References:
JP2014514302A
JP2014506902A
Foreign References:
WO2014099788A1
WO2014099768A1
WO2014093190A1
WO2012138734A1
WO2008133274A1
Attorney, Agent or Firm:
Patent business corporation Tsukuni