Title:
ヘテロアリール及びそれらの使用
Document Type and Number:
Japanese Patent JP6609258
Kind Code:
B2
Abstract:
and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
Inventors:
Balasan, Induty.
Blackburn, chris
Shabari, Jeffrey Peas.
Tutor, Joe Hara
Chris, Courtney A.
D'Amore, Natalie
Fleming, Paul Yi.
Gigstad, Kenneth M.
Gipson, Christie.
Girard, Mario
Fu, Yombo
Lee, Janice
Lee, Gann
Rezai, Mansole
Shinchuck, Michael Dee.
Sorcy, Francois
Stroud, Stephen Gee.
Voss, Tricia Jay.
Won, tu-chin
Shu, Hi
Shu, Tian Lin
Yes, Intune
Blackburn, chris
Shabari, Jeffrey Peas.
Tutor, Joe Hara
Chris, Courtney A.
D'Amore, Natalie
Fleming, Paul Yi.
Gigstad, Kenneth M.
Gipson, Christie.
Girard, Mario
Fu, Yombo
Lee, Janice
Lee, Gann
Rezai, Mansole
Shinchuck, Michael Dee.
Sorcy, Francois
Stroud, Stephen Gee.
Voss, Tricia Jay.
Won, tu-chin
Shu, Hi
Shu, Tian Lin
Yes, Intune
Application Number:
JP2016546472A
Publication Date:
November 20, 2019
Filing Date:
January 13, 2015
Export Citation:
Assignee:
MILLENNIUM PHARMACEUTICALS, INC.
International Classes:
C07D213/75; A61K31/444; A61K31/4545; A61K31/496; A61K31/501; A61K31/506; A61K31/517; A61K31/5377; A61K31/541; A61K31/549; A61K31/554; A61K45/00; A61P7/02; A61P9/04; A61P9/10; A61P9/12; A61P29/00; A61P35/00; A61P37/02; A61P37/08; C07D213/76; C07D213/81; C07D401/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D491/107; C07D513/04; C07D515/04
Domestic Patent References:
JP2014500308A | ||||
JP2016516710A | ||||
JP2011500823A |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto