Title:
ストレプトコッカス ニューモニアエ（Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ）血清型４に対するワクチン
Document Type and Number:
Japanese Patent JP6622804
Kind Code:
B2
Abstract:
The present invention relates to synthetic saccharides of general formula (I) that are related to Streptococcus pneumoniae serotype 4 capsular polysaccharide and conjugates thereof. Said conjugate and a pharmaceutical composition containing said conjugate are useful for prevention and/or treatment of diseases associated with Streptococcus pneumoniae, and more specifically of diseases associated with Streptococcus pneumoniae serotype 4. Furthermore, the synthetic saccharides of general formula (I) are useful as marker in immunological assays for detection of antibodies against Streptococcus pneumoniae bacteria.
More Like This:
Inventors:
Sieberger Peter H.
Pereira Craney Revev
Anish Chuck Mukar
Gay snare andreas
Pereira Craney Revev
Anish Chuck Mukar
Gay snare andreas
Application Number:
JP2017531577A
Publication Date:
December 18, 2019
Filing Date:
May 15, 2015
Export Citation:
Assignee:
Max Plank Gesell Shaft Tour Federundel Wissenshakhten A Four
International Classes:
C07H15/04; A61K39/00; A61K39/09; A61K39/39; A61P11/00; A61P11/02; A61P19/02; A61P27/02; A61P27/16; A61P29/00; A61P31/04
Domestic Patent References:
| JP2019504017A | ||||
| JP2016530212A | ||||
| JP2016526564A | ||||
| JP2017532321A |
Other References:
Carbohydrate Research,1991年,221,95-121
Carbohydrate Research,1990年,198,353-357
Carbohydrate Research,1988年,184,279-284
Carbohydrate Research,1986年,145,175-191
Proceedings of the National Academy of Sciences,1970年,67(1),138-142
Infection and Immunity,1991年,59(8),2750-2757
DAVID L. KLEIN,PNEUMOCOCCAL CONJUGATE VACCINES: REVIEW AND UPDATE,MICROBIAL DRUG RESISTANCE,1995年,VOL:1,NR:1,PAGE(S):49 - 58,URL,http://online.liebertpub.com/doi/pdf/10.1089/mdr.1995.1.49
ACS Chemical Biology,2015年12月16日,11,335-344,ACS Chem. Biol. 2016, 11, 335-344
Angew. Chem. Int. Ed.,2015年 7月24日,54,10016-10019
Carbohydrate Research,1990年,198,353-357
Carbohydrate Research,1988年,184,279-284
Carbohydrate Research,1986年,145,175-191
Proceedings of the National Academy of Sciences,1970年,67(1),138-142
Infection and Immunity,1991年,59(8),2750-2757
DAVID L. KLEIN,PNEUMOCOCCAL CONJUGATE VACCINES: REVIEW AND UPDATE,MICROBIAL DRUG RESISTANCE,1995年,VOL:1,NR:1,PAGE(S):49 - 58,URL,http://online.liebertpub.com/doi/pdf/10.1089/mdr.1995.1.49
ACS Chemical Biology,2015年12月16日,11,335-344,ACS Chem. Biol. 2016, 11, 335-344
Angew. Chem. Int. Ed.,2015年 7月24日,54,10016-10019
Attorney, Agent or Firm:
Nagoya International Patent Service Corporation