Title:
フェノール可溶性モジュリン、δ毒素、スーパー抗原に由来するトキソイドペプチド、およびその融合物
Document Type and Number:
Japanese Patent JP6632974
Kind Code:
B2
Abstract:
The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides delta toxin and phenol-soluble modulin peptides as well as mutants, fragments, variants or derivatives thereof. The disclosure further provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal proteins, e.g., DT, PSM, alpha hemolysin, leukocidin, superantigen, or any fragments, variants, derivatives, or mutants thereof fused together as a single polypeptide in any order.
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Inventors:
Aman Mohammad Jabad
Adikali Rajan Prasad
Shrenin Sergey
Holzburg Frederick Wayne
Calousm Hattis
Adikali Rajan Prasad
Shrenin Sergey
Holzburg Frederick Wayne
Calousm Hattis
Application Number:
JP2016521549A
Publication Date:
January 22, 2020
Filing Date:
June 18, 2014
Export Citation:
Assignee:
Integrated Biotherapeutics, Incorporated
International Classes:
C07K14/195; A61K39/00; A61K39/02; A61K39/39; A61P11/00; A61P31/04; A61P37/04; A61P43/00; C07K19/00; C12N1/21; C12N5/10; C12N15/31; C12P21/02
Domestic Patent References:
| JP2002502363A | ||||
| JP2005524381A |
Foreign References:
| WO2000002523A1 |
Other References:
Indian. J. Microbiol.,2012年,vol.52, no.3,p.449-55
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto