Title:
腎臓関連抗原１に対する抗体およびその抗原結合性フラグメント
Document Type and Number:
Japanese Patent JP6650432
Kind Code:
B2
Abstract:
Novel antibodies and antigen binding fragments that specifically bind to KAAG1 and which may be used in the treatment, detection and diagnosis of cancer comprising KAAG1 -expressing cells are disclosed herein. Cells expressing the antibodies and antigen binding fragments as well as methods of detecting and treating cancer using the antibodies and fragments are also disclosed. Cancer indications which may benefit from such treatment or detection include ovarian cancer, renal cancer, lung cancer, colorectal cancer, breast cancer, brain cancer, and prostate cancer, as well as melanomas.
Inventors:
Jill Bernard Trenbrae
Anna N Moretis
Tryan Three
Mario Philillon
Anna N Moretis
Tryan Three
Mario Philillon
Application Number:
JP2017235147A
Publication Date:
February 19, 2020
Filing Date:
December 07, 2017
Export Citation:
Assignee:
A Day T Therapeutics S.A.
International Classes:
C07K16/28; A61K39/395; A61P35/00; A61P35/02; A61P35/04; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12P21/08; G01N33/574
Domestic Patent References:
| JP2010513306A |
Foreign References:
| WO2010060186A1 | ||||
| WO2011004028A1 | ||||
| WO2010096434A1 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe