Title:
多量体の標的分子の検出に対する粒子ベースの試験において凝集を防ぐ試薬、方法及び装置
Document Type and Number:
Japanese Patent JP6746866
Kind Code:
B2
Abstract:
Methods for preventing aggregation of detection particles in a test for detecting a multi-epitope target analyte comprising two or more similar or identical epitopes in a sample and/or for determining the concentration of the multi-epitope target analyte in a sample by applying a first capture entity which can specifically bind to at least one epitope on the multi-epitope analyte and block the at least one epitope from binding to a detection particle. The detection of the multi-epitope target analyte may further include the use of a second capture entity, which can specifically bind to the same or a similar epitope of the multi-epitope target analyte as the first capture entity. The multi-epitope target may be detected through the use of a system comprising a sensor surface and the use of a first capture entity to block the at least one epitope from binding to a detection particle.
Inventors:
Eiffel, Tone Hendrik
Prince, Menno Willem Jose
Niwen Heiss, Yerun Hans
Prince, Menno Willem Jose
Niwen Heiss, Yerun Hans
Application Number:
JP2018197798A
Publication Date:
August 26, 2020
Filing Date:
October 19, 2018
Export Citation:
Assignee:
Mini Care Bee Buoy.
International Classes:
G01N33/543
Domestic Patent References:
| JP2012215553A | ||||
| JP2009525763A | ||||
| JP2005522698A | ||||
| JP2012230124A |
Foreign References:
| WO1992017781A1 |
Attorney, Agent or Firm:
Ikeda adult
Junichiro Sakamaki
Masakazu Noda
Junichiro Sakamaki
Masakazu Noda