Title:
ヒト細胞の単離のためのマウス細胞のディプリーション
Document Type and Number:
Japanese Patent JP6767737
Kind Code:
B2
Abstract:
Object of the invention is a process for depleting host cells from a xenograft of human cells on a murine host characterized in
9. fragmenting the xenograft into a sample comprising a single cell suspension
10. subjecting the sample to antibodies specific for a murine CD9 epitope coupled to a detection means
11. depleting the cell suspension from cells bound by the CD9-antibodies using the detection means
12. collecting the cells not bound by the CD9-antibodies as target cells.
Inventors:
Andreas Bozio
Olaf Heart
David Agorg
Olaf Heart
David Agorg
Application Number:
JP2015159850A
Publication Date:
October 14, 2020
Filing Date:
August 13, 2015
Export Citation:
Assignee:
Miltenyi Biotec GmbH
International Classes:
C12N5/09
Domestic Patent References:
| JP2013541504A |
Foreign References:
| WO2012141202A1 | ||||
| WO2013074596A1 |
Other References:
PNAS, 2012, 109(17):6662-6667
Stem Cells Translational Medicine, 2013, Vol.2, pp.233-242
Stem Cells Translational Medicine, 2013, Vol.2, pp.233-242
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Hiroyasu Ninomiya
Ueshima
Hiroyasu Ninomiya
Ueshima