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Title:
脂肪細胞とマクロファージの三次元共培養方法
Document Type and Number:
Japanese Patent JP6832912
Kind Code:
B2
Abstract:
The present invention relates to a three-dimensional co-culture of adipocytes and macrophages, wherein, in a hydrogel scaffold containing adipocytes and macrophages, the adipocytes and the macrophages are co-cultured to form a fat-like tissue, which can be then utilized in the studies and medicine development for treating metastatic diseases associated with adipose tissue.

Inventors:
Kim kiyun
Pakseum Bum
Lee sandals
Kim hiyun
Jun Won Hoon
Application Number:
JP2018502760A
Publication Date:
February 24, 2021
Filing Date:
July 22, 2016
Export Citation:
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Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
International Classes:
C12N5/077; C12M1/34; C12N5/0786; C12Q1/68; G01N33/50; G01N33/68
Domestic Patent References:
JP2010178701A
JP2009532054A
JP2010111585A
JP2013521033A
JP2014073107A
JP2015030848A
JP2014217375A
Foreign References:
WO2011155518A1
WO2014039429A1
WO2006112418A1
WO2007004635A1
Other References:
Biofabrication,2011年,Vol.3, No.1,p.1-9
Molecular Endocrinology,2009年,Vol.23, No.1,p.11-24
Arteriosclerosis, Thrombosis & Vascular Biology,,2005年,Vol.25, No.10,p.2062-2068
Clinical and Vaccine Immunology,,2010年,Vol.17, No.4,p.651-659
日本印刷学会誌,2011年,Vol.48, No.4,p.251-255
Tissue Enginieering,2011年,Vol.17, No.10,p.973-982
Attorney, Agent or Firm:
Masaki Hirota
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita