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Title:
血中循環腫瘍細胞に関する方法およびアッセイ
Document Type and Number:
Japanese Patent JP6912538
Kind Code:
B2
Abstract:
The technology described herein relates to methods of detecting circulating tumor cells (CTCs), e.g. by detecting changes in the expression of certain CTC marker genes. Aberrant expression of CTC marker genes, e.g. changes in expression indicative of CTCs can also be targeted in order to treat cancer.

Inventors:
Tin David Tea.
Harbor Daniel A.
Maheswaran Shamala
Application Number:
JP2019181785A
Publication Date:
August 04, 2021
Filing Date:
October 02, 2019
Export Citation:
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Assignee:
The General Hospital Corporation
International Classes:
C12Q1/6874; A61K31/7088; A61K39/395; A61K45/00; A61K48/00; A61P1/18; A61P35/00; C07K16/18; C12N15/12; C12Q1/04; C12Q1/6806; C12Q1/6837; C12Q1/6841; C12Q1/6851; C12Q1/686; G01N33/53; G01N33/574; G01N37/00
Domestic Patent References:
JP2006519616A
Foreign References:
WO2011112903A1
WO2009051734A1
US20120009582
WO2013134649A1
Other References:
American Journal of Pathology,2000年,Vol.157, No.4,p.1299-1309
Nature,2012年,Vol.487,p.510-513
British Journal of Cancer,2012年,Vol.106,p.508-516
Oncology,2012年,Vol.82, No.1,p.3-10
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto