Title:
ヒトＩＬ－１βに結合する抗体、その調製方法及び用途
Document Type and Number:
Japanese Patent JP7256266
Kind Code:
B2
Abstract:
Disclosed is an antibody of an entirely new structure that can bind to human IL-1β, or an antigen binding fragment thereof, which has a good biological function of blocking the binding of IL-1β to receptors thereof and thereby down regulate the activity of IL-1β, and can be used to prepare drugs for the treatment of immune diseases (such as arthritis, osteoporosis, and tumor necrosis factor receptor-associated periodic syndrome) mediated by IL-1β overexpression, and so has good prospects for clinical application.
Inventors:
夏瑜
王忠民
張鵬
李百勇
王忠民
張鵬
李百勇
Application Number:
JP2021523978A
Publication Date:
April 11, 2023
Filing Date:
November 04, 2019
Export Citation:
Assignee:
沢達生物医薬有限公司
International Classes:
C12N15/13; A61K39/395; A61P17/06; A61P19/02; A61P19/10; A61P37/00; C07K16/24; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/08
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