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Title:
治療薬剤の発見および分析のためのプラットフォーム
Document Type and Number:
Japanese Patent JP7478174
Kind Code:
B2
Abstract:
A method of characterizing candidate agents including steps of (a) providing a library of candidate agents attached to nucleic acid tags; (b) contacting the library with a solid support to attach the candidate agents to the solid support, whereby an array of candidate agents is formed; (c) contacting the array with a screening agent, wherein one or more candidate agents in the array react with the screening agent; (d) detecting the array to determine that at least one candidate agent in the array reacts with the screening agent; (e) sequencing the nucleic acid tag to determine the tag sequences attached to candidate agents in the array; and (f) identifying the at least one candidate agent in the array that reacts with the screening agent based on the tag sequence that is attached to the at least one candidate agent.

Inventors:
Mollyhe
Michael Prebyte
Misha Gorinski
Matthew Williamsonger
Sergio Peisajobic
Jonathan Mark Walter
Application Number:
JP2022014932A
Publication Date:
May 02, 2024
Filing Date:
February 02, 2022
Export Citation:
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Assignee:
Iramina Incorporated
International Classes:
C12M1/00; C12Q1/02; C12Q1/25; C12Q1/37; C12Q1/42; C12Q1/48; C12Q1/6816; C12Q1/6844
Domestic Patent References:
JP2011516072A
Foreign References:
WO2013096777A2
Attorney, Agent or Firm:
Kenji Sugimura
Mitsutsugu Sugimura
Takao Inoue