【発明の名称】第VIII:c因子型タンパク質の改良生産方法

Title:

【発明の名称】第VIII:c因子型タンパク質の改良生産方法

Document Type and Number:

Japanese Patent JPH02503744

Kind Code:

A

Abstract:

An improved method for producing Factor VIII:c-type proteins is disclosed which involves culturing mammalian cells which are capable of expressing the protein. In accordance with this invention the cells are cultured in a medium containing an effective amount of a substance comprising (a) von Willebrand Factor-type protein, (b) a phospholipid or phospholipid mixture, or a mixture of (a) and (b).

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Inventors:

Kauffman, Randall J.
Adamson, S Robert

Application Number:

JP50343688A

Publication Date:

November 08, 1990

Filing Date:

April 06, 1988

Export Citation:

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Assignee:

Genetics Institute, Inc.

International Classes:

C07K14/755; C12N15/09; C12N15/12; C12P21/02; A61K38/00; C12R1/91; (IPC1-7): C12N15/12; C12P21/02

Attorney, Agent or Firm:

Aoyama Ryo (1 person outside)

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