Title:
【発明の名称】生体活性組成物
Document Type and Number:
Japanese Patent JPH06501029
Kind Code:
A
Abstract:
An improved bioactive agent delivery composition and method of application are described. The composition comprises a bioactive agent, a hydrophilic polymer in an incompletely hydrated state and a substantially water-miscible solvent system. The agent and polymer are essentially dissolved in the solvent system to form a sprayable composition having a viscosity of less than 350 cP. Upon dilution with water, the viscosity of the composition increases to in excess of 1000 cP to produce a retentive coating at the site of application which provides enhanced bioavailability of the agent.
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Inventors:
アミドン,ゴードン,エル
チャンドラセカラン,ラマチャンドラン
ゴールドバーグ,アーサー,エイチ
チャンドラセカラン,ラマチャンドラン
ゴールドバーグ,アーサー,エイチ
Application Number:
JP50153593A
Publication Date:
January 27, 1994
Filing Date:
June 17, 1992
Export Citation:
Assignee:
アミドン,ゴードン,エル
チャンドラセカラン,ラマチャンドラン
ゴールドバーグ,アーサー,エイチ
チャンドラセカラン,ラマチャンドラン
ゴールドバーグ,アーサー,エイチ
International Classes:
A01N25/02; A01N25/10; A01N25/24; A61K9/00; A61K47/30; A61K47/32; A61K47/38; C08L1/00; C08L1/08; C08L33/00; C08L33/02; C08L71/02; (IPC1-7): A01N25/10; C08L71/02; C08L33/00; C08L1/08; A61K47/30; A01N25/02
Attorney, Agent or Firm:
北村 修