Title:
【発明の名称】鎮痙活性を有する3-[2-クロロ-4-(トリフルオロメチル)フェノキシ]-1-アゼチジンカルボキシアミド
Document Type and Number:
Japanese Patent JPH06503324
Kind Code:
A
Abstract:
The present invention relates to novel 3-(2-chlor-4-trifluoromethylphenoxy)-1-azetidine carboxamides having the formula: wherein R1 and R2, same or different, are selected from hydrogen, C1-C4 alkyl, and allyl. In a series of 3-(substitutedphenoxy)-1-azetidinecarboxamides, introduction of a chlorine atom at the 2-position of the phenoxy group of the corresponding 4-trifluoromethylphenoxy-1-azetidinecarboxamides resulted in unexpected increased potency in anticonvulsant pharmacological tests.
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Inventors:
Taylor, Chandler Roy, Junior
Kale, Albert Duncan, Junior
Stauffer, Harold Fisher, Junior
Kale, Albert Duncan, Junior
Stauffer, Harold Fisher, Junior
Application Number:
JP50109292A
Publication Date:
April 14, 1994
Filing Date:
November 14, 1991
Export Citation:
Assignee:
H.H.Robbins Company, Inc.
International Classes:
A61K31/397; A61P25/08; A61K31/40; C07D205/04; (IPC1-7): C07D205/04; A61K31/40
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)